| Identifier | HPI044985 |
| Interaction | K-ras <==> p53 |
| Role & State | RS:0000080,suppressor; |
| Interaction Type | IT:0000089,addition; |
| Biological Process | BP:0016446,mutation; |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 11696422_5, In addition, we analyzed the pancreatoblastomas for alterations found in adult-type pancreatic ductal adenocarcinomas including mutations in the K-ras oncogene and the p53 and DPC4 tumor suppressor genes, using direct DNA sequencing of exon 1 of K-ras and immunohistochemistry for p53 and Dpc4. |
| Reference | 11943721_6, In addition, we analyzed the SPTs for genetic alterations commonly found in pancreatic ductal adenocarcinomas, including mutations in the K-ras oncogene and p53 and DPC4 tumor suppressor genes, using direct DNA sequencing of K-ras and immunostaining for p53 and Dpc4. |