Identifier | HPI051880 |
Interaction | Mnt <==> p53 |
Role & State | RS:0000002,activity; |
Interaction Type | IT:0000372,treatment; IT:0000271,express; |
Biological Process | BP:0006915,apoptosis; |
Biological Function | BF:0010843,promoter activity; |
Subcelluar Location | --- |
Detection Method | --- |
Reference | 19086036_11, Lowering Mnt expression further enhanced LCA's inductive effect on p53 and cyclin D1.
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Reference | 19086036_9, Lithocholic acid (LCA) treatment of primary human hepatocytes and HuH-7 cells induced a similar switch from Mnt to Myc and increased p53 and cyclin D1 promoter activity and endogenous p53 and cyclin D1 expression and apoptosis.
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