| Identifier | HPI052824 |
| Interaction | NAG-1 <==> p53 |
| Role & State | --- |
| Interaction Type | --- |
| Biological Process | BP:0032502,development; BP:0006915,apoptosis; |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 18202802_10, Although further studies are needed to prove that an increased expression of Egr-1 by PTX-2 directly leads to NAG-1 induction and then apoptosis induction in p53-deficient Hep3B cells, the results of this study suggest that PTX-2 may be a good candidate for the development of a potential anti-tumorigenic agent in p53-deficient tumors. |