Detail information of PPI "HPI054177"

IdentifierHPI054177
InteractionNQO2  <==>  p53
Role & State        ---
Interaction TypeIT:0000287,activate; IT:0000202,stabilize;
Biological Process        ---
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference17545619_8, Further studies revealed that acute exposure to radiation or chemical leads to induction of NQO1 and NQO2 that stabilizes and transiently activates p53 and downstream genes.
Reference17545619_9, These results suggest that stress-induced NQO1 and NQO2 transiently stabilize p53, which leads to protection against adverse effects of stressors.