Identifier | HPI054177 |
Interaction | NQO2 <==> p53 |
Role & State | --- |
Interaction Type | IT:0000287,activate; IT:0000202,stabilize; |
Biological Process | --- |
Biological Function | --- |
Subcelluar Location | --- |
Detection Method | --- |
Reference | 17545619_8, Further studies revealed that acute exposure to radiation or chemical leads to induction of NQO1 and NQO2 that stabilizes and transiently activates p53 and downstream genes.
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Reference | 17545619_9, These results suggest that stress-induced NQO1 and NQO2 transiently stabilize p53, which leads to protection against adverse effects of stressors.
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