Detail information of PPI "HPI059744"

IdentifierHPI059744
InteractionPLK1  <==>  p53
Role & State        ---
Interaction TypeIT:0000079,suppression;
Biological ProcessBP:0000279,M phase; BP:0006915,apoptosis; BP:0007049,cell cycle;
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference20112253_8, In particular, suppression of PLK1 resulted in a block in the G2/M phase of the cell cycle and in massive apoptosis of HCC cells in vitro regardless of p53 status.