Identifier | HPI059744 |
Interaction | PLK1 <==> p53 |
Role & State | --- |
Interaction Type | IT:0000079,suppression; |
Biological Process | BP:0000279,M phase; BP:0006915,apoptosis; BP:0007049,cell cycle; |
Biological Function | --- |
Subcelluar Location | --- |
Detection Method | --- |
Reference | 20112253_8, In particular, suppression of PLK1 resulted in a block in the G2/M phase of the cell cycle and in massive apoptosis of HCC cells in vitro regardless of p53 status. |