Identifier | HPI061236 |
Interaction | PTEN promoter <==> p53 |
Role & State | --- |
Interaction Type | IT:0000059,binding; IT:0000068,transcription; |
Biological Process | --- |
Biological Function | BF:0002039,p53 binding; |
Subcelluar Location | --- |
Detection Method | --- |
Reference | 12839924_9, However, we confirmed that the binding of the p53 protein to p53 binding site-oligo of PTEN promoter is decreased in HBx-transfected liver cells by electrophoretic mobility shift analysis and, in addition, that HBx disrupts p53-mediated PTEN transcription, as evidenced by a PTEN promoter assay. |