Detail information of PPI "HPI062267"

IdentifierHPI062267
InteractionPkd1  <==>  p53
Role & State        ---
Interaction TypeIT:0000114,activation; IT:0000077,regulate; IT:0000258,prevent;
Biological Process        ---
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference15761494_0, Pkd1 regulates immortalized proliferation of renal tubular epithelial cells through p53 induction and JNK activation.
Reference15761494_10, Thus, Pkd1 plays a role in preventing immortalized proliferation of renal tubular epithelial cells through the induction of p53 and activation of JNK.